Introduction: In the current era, with the increasing pressures of modern lifestyles, mental health has gained paramount importance as a cornerstone of quality of life and social cohesion. This research aims to explore the capacities of Surah Al-Fatiha in enhancing psychological well-being and to present a framework based on divine teachings for addressing mental health challenges.

Methods: This study employed a qualitative approach using a descriptive-analytical content analysis method. Data were gathered through the study of Quranic exegeses (focusing on Surah Al-Fatiha), previous research on mental health from an Islamic perspective, and scientific psychological resources. In the analysis phase, key concepts related to mental health within Surah Al-Fatiha were extracted, and their themes were aligned with established psychological principles and theories of mental health.

Findings: The results of the qualitative content analysis of Surah Al-Fatiha’s verses led to the extraction of key mental health-related concepts, including seeking help, reliance on God, gratitude and praise of God, Lordship, the hereafter, divine guidance, and servitude. These teachings significantly contribute to improving various dimensions of mental health by strengthening the meaning of life, purposefulness, self-esteem, responsibility, self-confidence, moderation, role modeling, social cognition, and positive relationships.

Conclusion: The present research indicates that Surah Al-Fatiha encompasses significant psychological concepts with the potential to enhance psychological well-being and individual growth. Further in-depth study of these concepts and the utilization of empirical approaches to measure their effectiveness can pave the way for developing psychological interventions based on Islamic teachings.